Big Data

For Better Hearts

BigData@Heart

Publications

 

Research papers

 

 

  1. Sonia Shah. Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature Communications. 09 January 2020. doi.org/10.1038/s41467-019-13690-5 
     
  2. Shona Kalkman. Responsible data sharing in a big data-driven translational research platform: lessons learned. BMC Medical Informatics and Decision Making. 30 December 2019. doi.org/10.1186/s12911-019-1001-y
     
  3. Daniel M. Bean. Semantic computational analysis of anticoagulation use in atrial fibrillation from real world data. Plos One. 25 November 2019. doi.org/10.1371/journal.pone.0225625 
     
  4. Laura Pasea. Bleeding in cardiac patients prescribed antithrombotic drugs: Electronic health record phenotyping algorithms, incidence, trends and prognosis. BMC Medicine. 20 November 2019. doi.org/10.1186/s12916-019-1438-y 
     
  5. Shona Kalkman. Patients’ and public views and attitudes towards the sharing of health data for research: a narrative review of the empirical evidence. Journal of Medical Ethics. 12 November 2019. http://dx.doi.org/10.1136/medethics-2019-105651  
     
  6. Schrage B, Uijl A, Benson L, Westermann D, Ståhlberg M, Stolfo D, Dahstrom U, Linde C, Braunschweig F, and Savarese G. Association between use of primary prevention implantable cardioverter-defibrillators and mortality in patients with heart failure. A prospective propensity-score matched analysis from the Swedish heart failure registry. Circulation-Heart Failure. 3 September 2019. doi.org/10.1161/CIRCULATIONAHA.119.043012
     
  7. Stolfo D, Uijl A, Schrage B, Fudim M, Asselbergs FW, Koudstaal S, Sinagra G, Dahlstrom U, Rosano G, and Savarese G. Association between beta-blocker use and mortality/morbidity in older patients with heart failure with reduced ejection fraction. A propensity score-matched analysis from the Swedish Heart Failure Registry. European Journal of Heart Failure. 3 September 2019. https://doi.org/10.1002/ejhf.1615
     
  8. Banerjee A, Allan V, Denaxas S, Shah A, Kotecha D, Lambiase PD, Jacob J, Lund LH,Hemingway H. Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis. Europace. 2019 July 14. doi.org/10.1093/europace/euz220
     
  9. Spiros Denaxas. UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER. Journal of the American Medical Informatics Association. 22 July 2019. doi.org/10.1093/jamia/ocz105 
     
  10. Shah S, Henry A, Roselli C, et al. Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure. BioRivix, 2019 July 10. doi.org/10.1101/682013
     
  11. Elias Allara. Genetic determinants of lipids and cardiovascular disease outcomes: a wide-angled Mendelian randomization investigation​. BioRxiv, 14 June 2019. doi.org/10.1101/668970 

  12. Kalkman S, Mostert M, Gerlinger C, Van Delden JJM, Van Thiel GJMW. Responsible data sharing in international health research: a systematic review of principles and norms. BMC Medical Ethics. 2019 March 28. doi.org/10.1186/s12910-019-0359-9
     
  13. Uijl A, Koudstaal S, Direk K, Denaxas S, Groenwold RHH, Banerjee A, Hoes AW, Hemingway H, Asselbergs FW. Risk factors for incident heart failure in age‐ and sex‐specific strata: a population‐based cohort using linked electronic health records. European Journal of Heart Failure. 2019 January 07. doi.org/10.1002/ejhf.1350
     
  14. Van der Laan SW, Harshfield EL, Hemerich D, Stacey D, Wood AM, Asselbergs FW. From lipid locus to drug target through human genomics. Cardiovascular Research. 2018 July 15. doi:10.1093/cvr/cvy120
     
  15. Johannes M I H Gho, An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors. BMJ Open. 2018 March 03. doi.org/10.1136/bmjopen-2017-018331 
     
  16. Hemingway H, Asselbergs FW, Danesh J, Dobson R, Maniadakis N, Maggioni A, van Thiel GJM, Cronin M, Brobert G, Vardas P, Anker SD, Grobbee DE, Denaxas S. Big data from electronic health records for early and late translational cardiovascular research: challenges and potential. European Heart Journal. 2017 August 29. doi:10.1093/eurheartj/ehx487
     
  17. Anker S, Asselbergs FW, Brobert G, Vardas P, Drobbee DE, Cronin M. Big Data in Cardiovascular Disease. European Heart Journal. 2017 June 21. doi: 10.1093/eurheartj/ehx283.